Spindle cell tumor, pigmented - Altmeyers Encyclopedia

History
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Reed, 1975

Definition
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Benigner, pigmentary tumor of the skin occurring in young people, sex of the patient often female, histologically close to the Spitz nevus.

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Manifestation
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Occurring between the ages of 10 and 40.

Localization
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Mostly located on the extremities, especially the legs.

Clinical features
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Macular to plaque-shaped, sharply defined, homogeneously dark pigmented tumour with irregular, mostly scaly surface. Diameter mostly < 6 mm. Often rapid growth.

Histology
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Junction nevus, consisting of characteristic, clearly pigmented, uniform spindle cells, which lie nestlike confluent in the epidermis-dermis area. Formation of fascicular structures that displace the corial connective tissue in a nodular manner.

Differential diagnosis
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Malignant melanoma; Spitz nevus; dysplastic melanocytic nevus.

Therapy
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S.u. Naevus Spitz.

Literature
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Cerroni L, Kerl H (2001) Tutorial on melanocytic lesions. At J Dermatopathol 23: 237-241
Gartmann H (1981) The pigmented spindle cell tumor. Z Hautkr 56: 862-876
Kolde G et al (1987) The pigmented spindle cell tumor. Dermatologist 38: 743-745
Reed RJ et al (1975) Common and uncommon melanocytic nevi and borderline melanomas. Sem Oncol 2: 119-147
Ruiter DJ (2003) Current diagnostic problems in melanoma pathology. Seminar Cutan Med Surg 22: 33-41