Synonym(s)
Stibogluconate sodium
DefinitionThis section has been translated automatically.
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Sodium ibogluconate is a pentavalent antimony derivative that induces apoptosis in Leishmania. Retrospective studies show that the preparation is highly effective (Fischer T et al. 2024).
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IndicationThis section has been translated automatically.
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Visceral leishmaniasis (L. donovani): 10-20 mg/kg bw/day i.v. (less painful) or i.m. for 20-30 days.
Oriental leishmaniasis (L. tropica): 20 mg/kg bw/day i.v. (less painful) or i.m. for 20-30 days.
Mucocutaneous leishmaniasis: 20 mg/kg bw/day i.v. or i.m. for 20-30 days.
Undesirable effectsThis section has been translated automatically.
Cave! The active ingredient is extremely cardiotoxic when used systemically!
PreparationsThis section has been translated automatically.
Pentostam® (only available from international pharmacies).
LiteratureThis section has been translated automatically.
- Fischer T et al. (2024)Treatment of mucocutaneous leishmaniasis- a systematic review. JDDG 22:763-774
Prof. Dr. med. Peter Altmeyer