Serum test, autologous

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 21.04.2021

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Synonym(s)

ASST; Autologous plasma skin test; Autologous plasma test; Autologous serum test; Plasmatest autologous

Definition
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Test procedure for the diagnosis of autoreactive, chronic urticaria.

General information
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However, the result of this study showed that the autologous serum test and ASST seem to be equivalent.

Indication
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Implementation
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Blood collection in sterile tubes without anticoagulant

After 30 min. blood clotting at room temperature, remove by centrifugation at 450-500g for 10 min.

Intracutaneous test (0.05ml undiluted autologous serum) on the skin of the flexor-sided forearm

Control with physiological saline solution and 0.05ml 0.5-1.0 ug histamine solution

After 30 min. determination of the respective square diameters

Positive autologous serum test: Quaddle diameter (autologous serum) - Quaddle diameter (NaCl) >1.5mm (requirement: histamine control = positive)

Literature
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  1. Yildiz, O. et al (2011) Evaluation of autologous plasma skin test in patients with chronic idiopathic urticaria. Br. J. Dermatol 165:1205-1209

Outgoing links (1)

Urticaria (overview);

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Last updated on: 21.04.2021