DefinitionThis section has been translated automatically.
Immunoglobulin A (IgA) deficiency-2 (IGAD2) is caused by a heterozygous, homozygous, or compound heterozygous mutation in the TNFRSF13B gene (604907), which encodes transmembrane activator and CAML interactor (TACI) on chromosome 17p11.2. A mutation in the TNFRSF13B gene can also cause common variable immunodeficiency-2 (CVID2; 240500).
