Sebaceous gland hyperplasia neonatal L73.9

Seboglandular proliferation disorder with formation of 2-5 mm large yellow papules and seborrhea.

Present in more than 50% of newborns. The prevalence correlates with the degree of maturity, thus less frequent in premature babies.

Stimulation of the sebaceous gland follicles by maternal androgens. Due to persistent androgenic stimuli, sebaceous gland hyperplasia is more frequent and longer lasting in breastfed children. It usually subsides after 4-6 months.

Located mainly centrofacially, preferably on the bridge of the nose, forehead or cheeks.

Isolated standing or disseminated sowing of densely aggregated, 0.2-0.5 cm large, skin-coloured or yellowish-reddish, centrally slightly dented papules. Mostly accompanied by seborrhoea (Seborrhoea oleosa).

Milia: no centrofacial accentuation; roundish with firm consistency

Acne infantum: centrofacial stress; inflammatory; pustular

Pityrosporum folliculitis of the infant: acute follicular pustules, face, neck, capillitium

Treatment not necessary.

1. Kaufmann R (1987) Diffuse (presenile) sebaceous gland hyperplasia, a new entity? dermatologist 38: 31-35
2. Zouboulis C et al (2003) Ciclosporin A - induced sebaceous glands hyperplasia. Br J Dermatol 149: 198-200