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SebaceomaD23.L2
Synonym(s)
sebaceoma; sebaceous epithelioma; Sebazeoma
DefinitionThis section has been translated automatically.
Controversial term (especially in the Anglo-American language area) for adnexal tumors with differentiation of sebaceous glands, which show only a moderate degree of differentiation. Nosologically they are located between the sebaceous adenoma and the sebaceous carcinoma. Sebaceous epitheliomas often occur in a sebaceous nevus.
ManifestationThis section has been translated automatically.
Predominantly occurring after the age of 50. Men are more frequently affected than women.
LocalizationThis section has been translated automatically.
Located mainly on the face and ear region.
Clinical featuresThis section has been translated automatically.
Clinically uncharacteristic 0.5-12.0 cm large, skin-coloured or slightly yellowish lumps. The diagnosis is usually a random histological finding.
HistologyThis section has been translated automatically.
Well-defined, cell-rich, dermal tumor with barely recognizable differentiation of the sebocytes. Basoid, basophilic seboblastic cells predominate. Mitosis occurs. In the parenchyma there are irregularly distributed, partially cystically dilated duct structures.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Excision in healthy individuals with a small safety margin.
LiteratureThis section has been translated automatically.
- Betti R et al (2001) Sebaceoma arising in association with seborrheic keratosis. At J Dermatopathol 23: 58-561
- Horio T et al (2003) Photodynamic therapy of sebaceous hyperplasia with topical 5-aminolaevulinic acid and slide projector. Br J Dermatol 148: 1274-1276
- Kaddu S et al (1999) Trichoblastoma and sebaceoma in nevus sebaceus. At J Dermatopathol 21: 552-556
- Kruse R et al (2003) Frequency of microsatellite instability in unselected sebaceous gland neoplasias and hyperplasias. J Invest Dermatol 120: 858-864
- Luba MC et al (2003) Common benign skin tumors. On Fam Physician 67: 729-738
- Misago N et al (2002) Sebaceoma and related neoplasms with sebaceous differentiation: a clinicopathologic study of 30 cases. At J Dermatopathol 24: 294-304
- Misago N et al (2001) Sebaceous carcinoma, trichoblastoma, and sebaceoma with features of trichoblastoma in nevus sebaceus. At J Dermatopathol 23: 456-462
- Misago N et al (2001) Rippled-pattern sebaceoma. At J Dermatopathol 23: 437-443