Scedosporium infectionB45.9
Synonym(s)
DefinitionThis section has been translated automatically.
Rare, often lethal (opportunistic) mould infection in immunocompromised patients by S. prolificans and S. apiopspermum (anamorphic form; teleomorphic: Pseudallescheria boydii ).
Occurrence/EpidemiologyThis section has been translated automatically.
Affected are mainly haemato-oncological patients and patients after solitary organ transplants (Caroti L et al. 2010). As a risk factor, the application of glucocorticoids is considered the most important. In recent years, the importance of colonization of the respiratory tract of patients with perennial cystic fibrosis (CF) has been increasingly pointed out and warned against lung transplantation in P. boydii colonized CF patients.
Clinical featuresThis section has been translated automatically.
Localized manifestation with formation of fungal ganulomas in skin (formation of subcutaneous nodules), eye, joints and respiratory tract.
Generalized manifestation: Fungemia with fever, myalgia and hematogenic organ manifestation.
TherapyThis section has been translated automatically.
Alternative: liposomal amphotericin B
Note(s)This section has been translated automatically.
For several decades, as in fusariosis, a change in infection localization from localized mycetic lesions in immunocompetent patients after traumatic pathogen inoculation to systemic and disseminated infections in immunocompromised patients has been observed.
LiteratureThis section has been translated automatically.
- Caroti L et al (2010) Subcutaneous nodules and infectious complications in renal allograft recipients. Transplant proc 42:1146-1147.
- Solé A Scedosporium apiospermum disseminated infection in a single lung transplant recipient. Rev Iberoam Micol 28:139-142.