DefinitionThis section has been translated automatically.
Histologic variant of adult xanthogranuloma with predominance of stellate-cephalic macrophages in the fine epithelial substrate.
ManifestationThis section has been translated automatically.
Young adults
You might also be interested in
LocalizationThis section has been translated automatically.
In one of this retrospective clinicopathologic study, "scalloped -cell -xanthogranuloma" occurred mostly on the back or head and neck of young adult males.
Clinical featuresThis section has been translated automatically.
Yellow or red papules and nodules with a diameter of 0.5-1.0cm. These are usually diagnosed as melanocytic nevi, pigmented fibromas or basal cell carcinomas.
HistologyThis section has been translated automatically.
Histology characteristically showed a planar infiltrate of predominantly scalloped histiocytes (> 79% of all cell types) in the upper dermis. Other mononuclear (vacuolated, xanthomatized, spindle-shaped, oncocytic) and multinucleated (foreign body and touton) histiocytes were also regularly observed.
Immunohistochemically, cases exhibit a macrophagocytic/dendritic cell lineage, with positivity for CD68, KiM1p, HAM 56, and factor XIIIa .
Ultrastructurally, numerous intracytoplasmic dense, occasionally myeloid corpuscles are found present.
LiteratureThis section has been translated automatically.
- Calonje E et al (2020) Cutaneous lymphoproliferative diseases and related disorders. In: McKee's Pathology of the Skin: Xanthoma disseminatum and scalloped cell xanthogranuloma.
- Zelger BG et al (1998) Scalloped cell xanthogranuloma. Histopathology 32:368-374.
Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.