Rucinol

Author:Prof. Dr. med. Peter Altmeyer

Last updated on: 29.10.2020

Synonym(s)

4-Butyl-benzol-1,3-diol; 4-n-butylresorcinol

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DefinitionThis section has been translated automatically.

Synthetic resorcinol compound used as an active ingredient in the treatment of hyperpigmentation of the skin. Rucinol inhibits tyrosinase, the key enzyme in melanin synthesis. Furthermore it inhibits TRP-1, the tyrosinase-related protein-1. The effect of rocinol on the melanin production seems to be considerably stronger than that of hydroquinone and kojic acid.

IndicationThis section has been translated automatically.

hyperpigmentation of the skin; chloasma, lentigo solaris, lentigo senilis

Note(s)This section has been translated automatically.

In Germany, cosmetics containing rocinol have been available in the form of serum and cream since January 2005. The effectiveness and tolerance of the substance has been proven by several clinical studies.

LiteratureThis section has been translated automatically.

Khemis A et al (2007) Evaluation of efficacy and safety of rucinol serum in patients with melasma: a randomized controlled trial. Br J Dermatol 156:997-1004
Konda S et al (2012 New horizons in treating disorders of hyperpigmentation in skin of color. Semin Cutan Med Surg 31:133-139

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer