Synonym(s)
Area of evenly arranged dotted or polymorphous capillaries
DefinitionThis section has been translated automatically.
Reflected light microscopic structural feature of malignant melanomas with a specificity of more than 85%.
General informationThis section has been translated automatically.
Reflected light microscopy: The round or oval zones built up from evenly distributed vessels show reduced background pigmentation or none at all. The areas are often the starting point of a nodular part of the lesion. Polymorphic vascular figures resemble Greek small letters (minuscule). In initial lesions, they are fine caliber, not knotty branched and punctually dilated. Older foci show an increase in neovascularisation with aneurysmatic vascular sacculations and strong calibre fluctuations. A binding to dermal papillae is no longer recognizable, since newly formed proliferating vessels exceed predetermined microanatomical structures.
OccurrenceThis section has been translated automatically.
In about 30% of malignant melanomas from a Clark Level III.
LiteratureThis section has been translated automatically.
- Kreusch JF (2003) Vascularization patterns of pigmented and non-pigmented skin tumors. In: Blum A, Kreusch JF, Bauer J, Garbe C (Hrsg) Dermatoscopy of skin tumors. Steinkopff, Darmstadt, S. 59-66
- Menzies SW, Ingvar C, McCarthy WH (1996) A sensitivity and specificity analysis of the surface microscopy features of invasive melanoma. Melanoma Res 6: 55-62
- Schulz H (2002) Reflected light microscopic vital histology. Springer, Berlin Heidelberg New York
Prof. Dr. med. Peter Altmeyer
