Pyoderma, chancre L08.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 14.06.2022

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Synonym(s)

pyodermia chancriformis

History
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Covisa and Berjarano 1927

Definition
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Chronic pyoderma reminiscent of syphilitic primary (chancre). The diagnosis has largely lost its significance in international literature.

Pathogen
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Especially staph.

Localization
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Especially eyes, beard area, lower lip, also eyelashes, cheeks, buttocks, genitals are affected.

Clinical features
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Derby, well demarcated, raised above the skin level, associated with vigorous inflammatory collateral edema, initially superficially eroded, later ulcerated, mies only slightly painful, crusted infiltrate. Regional moderately ductal swelling of the lymph nodes.

Differential diagnosis
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Ulcus durum: syphilis serology; lymphadenopathy.

Anthrax of the skin: extremely rare; acute event. At the site of inoculation, development of a less conspicuous red spot: increasing infiltration with then rapid formation of an inflammatory nodule or pustule; rapid spread, hemorrhagic blister; blackish necrosis with considerable collateral swelling. Fever.

Ecthyma contagiosum: ulcers appearing as if punched out. Lower leg

cutaneous leishmaniasis: travel history (where the olive tree grows)

Keratoacanthoma: nodular lesion with central horny plug. No inflammatory quality

Lymphomatoid papulosis: marked chronicity; histology with CD30+proliferates is diagnostic (the forms of "chancroid pyoderma" depicted in many places often correspond to "lymphomatoid papulosis".

External therapy
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Adapted to the situation.

In an early phase of the disease, moist compresses with disinfecting solutions such as polihexanide (Serasept, Prontoderm), quinolinol (e.g., Chinosol 1:1000 or R042 ) or potassium permanganate (light pink) are useful.

Ointment dressings with disinfecting additives such as Polyvidon iodine ointment (e.g. Betaisodona® ointment).

In addition, wound treatment appropriate to the stage.

Internal therapy
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Antibiosis after antibiogram. Initial cephalosporins like ceftriaxone (e.g. Rocephin) 1 time 2 g/day i.v. or cefpodoxime (e.g. Orelox 200) 2 times/day 1 tbl. p.o. or flucloxacillin (e.g. Staphylex) 3 times 1.0 g/day p.o.

Literature
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  1. Hegemann B et al (2001) Recurrent chancriform mucous membrane ulcer in plasmacytoma with secondary IgA deficiency. Pyoderma chancriforme of the tongue. dermatologist 52: 820-823
  2. Klein CE et al (1990) Schankriform pyoderma. Dt Derm 38: 1119-1120

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 14.06.2022