Ptbp-f-r

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

p-tert-butylphenol formaldehyde resin

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OccurrenceThis section has been translated automatically.

  • PTBP-F-R is used in adhesives, especially for bonding leather and rubber products, because it adheres particularly well to their surfaces, is flexible and durable. Therefore PTBP-F-R can be found in corresponding leather products, i.e. in shoes, handbags, belts and watch straps.
  • Occupational exposures arise primarily during the bonding of leather in shoe factories and shoemaker's workshops. For more than 30 years PTBP-F-R has been known to be a frequent allergen for shoemakers.

EffectsThis section has been translated automatically.

  • A sensitization against PTBP-F-R is not caused by the through-polymerized resin but by low-molecular reaction products and only very rarely by the two basic chemicals formaldehyde and p-tert-butylphenol (PTBP).

Clinical pictureThis section has been translated automatically.

  • The allergic contact eczema caused by PTBP-F-R often appears clinically as hyperkeratotic-rhagadiform eczema of the fingers and palms.
  • In addition, the face may also be affected by a dislocated contact dermatitis due to allergen carry-over.

Note(s)This section has been translated automatically.

  • In the MdE assessment, the effects of a contact allergy to PTBP-F-R are usually only minor. However, if, for example, it is proven to be completely impossible for the person affected to wear safety shoes due to the sensitization to PTBP-F-R, the effects can also be higher.
  • In many cases, no information can be obtained as to whether a particular shoe contains PTBP-F-R or not; the selection of suitable shoes for patients with sensitization to PTBP-F-R is therefore often difficult.

LiteratureThis section has been translated automatically.

  1. Geier J et al (2010) Effect of occupational sensitization to p-tert-butylphenol formaldehyde resin (PTBP-F-R) at the BK 5101st Dermatol Occupation Environment 58:190-192

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Last updated on: 29.10.2020