Ptbp-f-r

Synonym(s)

p-tert-butylphenol formaldehyde resin

PTBP-F-R is used in adhesives, especially for bonding leather and rubber products, because it adheres particularly well to their surfaces, is flexible and durable. Therefore PTBP-F-R can be found in corresponding leather products, i.e. in shoes, handbags, belts and watch straps.
Occupational exposures arise primarily during the bonding of leather in shoe factories and shoemaker's workshops. For more than 30 years PTBP-F-R has been known to be a frequent allergen for shoemakers.

A sensitization against PTBP-F-R is not caused by the through-polymerized resin but by low-molecular reaction products and only very rarely by the two basic chemicals formaldehyde and p-tert-butylphenol (PTBP).

Internal medicine

Catecholamines (from Greek catechu = extract from the tiger accia, amine from Greek catecholamines) Ammon =...

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The allergic contact eczema caused by PTBP-F-R often appears clinically as hyperkeratotic-rhagadiform eczema of the fingers and palms.
In addition, the face may also be affected by a dislocated contact dermatitis due to allergen carry-over.

In the MdE assessment, the effects of a contact allergy to PTBP-F-R are usually only minor. However, if, for example, it is proven to be completely impossible for the person affected to wear safety shoes due to the sensitization to PTBP-F-R, the effects can also be higher.
In many cases, no information can be obtained as to whether a particular shoe contains PTBP-F-R or not; the selection of suitable shoes for patients with sensitization to PTBP-F-R is therefore often difficult.

Geier J et al (2010) Effect of occupational sensitization to p-tert-butylphenol formaldehyde resin (PTBP-F-R) at the BK 5101st Dermatol Occupation Environment 58:190-192