Pseudoepitheliomatous keratotic balanitis N48.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

balanitis keratotica et pseudoepitheliomatosa; balanoposthitis pseudoepitheliomatosa; pseudoepitheliomatous balanitis; Pseudoepitheliomatous keratotic and micaceous balanitis

History
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Civatte and Lortat-Jakob, 1961

Definition
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Very rare balanitis with development of papillomatous and hyperkeratotic growths on the glans penis and the prepuce. Possibly pre- or pseudocarcinosis as a preliminary stage of a spinocellular verrucous carcinoma. In some cases detection of HPV.

Histology
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Massive hyperkeratosis and pseudoepitheliomatous epidermal hyperplasia.

Differential diagnosis
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Verrucous carcinoma of the penis: clearly consistency increased lesion, histology is diagnostic.

Condylomata acuminata: rather soft, verrucous growths.

Papillae coronae glandis: completely asymptomatic single or multi-row, white, papillary protrusions.

Therapy
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Electrocaustic (laser therapeutic) removal after bioptic control. Follow-up treatment with 5-fluorouracil (Kim JY ett al. 2019).

Alternative: excision of the foci with histological diagnosis

Alternative: generous excision by experienced surgeons.

Circumcision should be performed in a 2nd step. Circumcision alone is not sufficient.

Progression/forecast
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Benign highly chronic course.

Post-op recurrences are not uncommon.

After a longer recurrent course (and resistance to therapy), danger of transition to an invasive verrucous carcinoma of the penis.

Literature
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  1. Kim JY ett al(2019) Surgical managements of pseudoepitheliomatous keratotic and micaceous balanitis:
    A case report. Int J Surg Case Rep 55:37-40.
  2. Lortate Jacob E, civatte J (1961) Balanite pseuso-épithéliomateuse, kératosique et micacée. Bull Soc Fr Dermatol 68: 164-167

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020