Progesterone

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 23.08.2021

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Synonym(s)

Progesterone

Definition
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Corpus luteum hormone.

Indication
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Menstrual disorders, amenorrhea, endometriosis, mastodynia.

Dosage and method of use
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After 2 weeks of pre-treatment with estrogens 5-10 mg i.m. for 6 days.

Standard concentration
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Apply 1% gel twice a day to each breast from the 10th to 25th day of the cycle.

Undesirable effects
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Most hormone preparations contain natural progesterone ("bioidentical progesterone") and are well tolerated. Common progesterone side effects include fatigue, drowsiness, dizziness, headaches and depressed mood. They occur in one in ten to one in a hundred patients.

Side effects are rare with topical use of progesterone-containing preparations. Skin rashes and itching are most commonly observed. Headache and fatigue occur less frequently.

In rare cases, panniculitis may develop at the site of injection (Xiao W et al. 2021).

Recipe(s)
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Preparations
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Progestogel, Crinone 8% vaginal gel, Utrogest Kps.

Literature
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  1. Xiao W et al. (2021) Panniculitis caused by progesterone injection can be treated by physical therapy. Dermatol Ther 34:e14501.

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Last updated on: 23.08.2021