DefinitionThis section has been translated automatically.
Broadband anthelmintic.
Half-lifeThis section has been translated automatically.
1–1,5 h
You might also be interested in
Pharmacodynamics (Effect)This section has been translated automatically.
Vermicide by spastic paralysis of the worm muscles, glucose and glycogen depletion.
IndicationThis section has been translated automatically.
Bilharzia (S. haematobium, S. mansoni, S. intercalatum, S. japonicum, S. mekongi), liver flukes (e.g. Clonorchis sinensis, Opisthorchis viverrini, O. felineus), pulmonary flukes (Paragonimus westermani anda. spp.), taeniasis, neurocysticercosis, Hymenolepis nana (dwarf tapeworm), Diphyllobothrium pacificum (South American fish tapeworm) (see tapeworms)
Limited indicationThis section has been translated automatically.
Restricted kidney function, cardiac arrhythmia, heart failure requiring digitalis.
Dosage and method of useThis section has been translated automatically.
See Table 1.
Note!
The therapy of cysticercosis should be carried out as an in-patient!Undesirable effectsThis section has been translated automatically.
Abdominal pain, nausea, vomiting, headaches, dizziness, weakness, fatigue, urticaria, temperature rise, urticaria, difficulty swallowing, possibly chest tightness
InteractionsThis section has been translated automatically.
Carbamazepine, cimetidine, dexamethasone and phenytoin lead to a reduction of the praziquantel level.
ContraindicationThis section has been translated automatically.
Pregnancy, breastfeeding (up to 48 hours after taking the tablet), ocular cysticercosis, liver diseases.
PreparationsThis section has been translated automatically.
Biltricides, Cesol, Cysticides
PatientinformationThis section has been translated automatically.
Remember! The tablets cause a restriction of the ability to react!
TablesThis section has been translated automatically.
Dosages of Praziquantel
Indication |
Dosage |
Leech | |
Clonorchis, Dicrocoellum, Fasciolopsis, Herterophyer, Metagonism, Opisthorchis |
3 times 25 mg/kg KG p.o. as ED |
Paragonism |
3 times 25 mg/kg bw/day for 2 days |
Coupled sails (schistosomes) | |
Sch. haematobium, intercalatum, mansoni |
2 times 20 mg/kg bw/day as ED |
Sh. japonicum |
3 times 20 mg/kg bw or 30 mg/kg bw as ED |
Sh. Mekongi | |
Tapeworms | |
Diphyllobothrium latum |
15 mg/kg bw as ED |
dipylidium caninum |
25 mg/kg bw as ED |
Hymenolepis nana and diminuta |
25 mg/kg bw as ED |
saginata taenia |
10 mg/kg bw/day for 1-3 days |
taenia solium |
10 mg/kg bw/day for 1-3 days |
Cysticercosis | |
Cysticercosis (except intraocular cysticercosis) |
50 mg/kg bw/day for 15 days |
Prof. Dr. med. Peter Altmeyer