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Pidobenzone

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

4-hydroxyphenyl ester; 4-Hydroxyphenyl ester; 5-oxo; CAS No: 138506-45-3; L-Proline; Pidobenzone

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DefinitionThis section has been translated automatically.

Pidobenzone, an amino acid ester of hydroquinone, is a topically applied active ingredient used for the treatment of melasma (chloasma).

Note(s)This section has been translated automatically.

The treatment of melasma with 4% pidobenzone is described as safe and effective. Allergic reactions have not been reported so far. However, there are no reliable results regarding the allergological relevance of the preparation. Especially in comparison to hydroquinone the advantages of the preparation are not clearly defined.

LiteratureThis section has been translated automatically.

Campanati A et al (2016) Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial. Dermatology 232:478-483.

Zanierei et al (2008): Melasma: successful treatment with pidobenzone 4% (K5lipogel) Dermatol Ther 21: Suppl 1, 18-19.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer