Pasqualini syndromeE23.0

Author:Prof. Dr. med. Peter Altmeyer

Last updated on: 29.10.2020

Synonym(s)

Eunuchism with spermiogenesis; Eunuchs fertile; Fertile eunuch syndrome

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HistoryThis section has been translated automatically.

Pasqualini and Bur, 1950

DefinitionThis section has been translated automatically.

Isolated deficiency of LH with normal FSH secretion due to incremental testicular dysfunction with secondary Leydig cell insufficiency.

Clinical featuresThis section has been translated automatically.

Eunuchism, large slender appearance without secondary sexual characteristics, almost normal testicle size

LaboratoryThis section has been translated automatically.

normo- to oligozoospermia ("fertile eunuchs"), LH and total gonadotropin excretion in urine reduced.

TherapyThis section has been translated automatically.

With entry into puberty hormone substitution. Initial testosterone cantate (e.g. Testoviron depot 50) i.m. 50 mg/month. Slowly increase dose within 1-2 years up to 250 mg every 2-3 weeks, e.g. testosterone cantate (e.g. Testoviron Depot 250).

LiteratureThis section has been translated automatically.

Pasqualini RQ, Bur EC (1950) Sindrome hipoandrogenico con gametogenesis conservada: clasificacion de la insuficiencis testicular. Rev Assoc Med Argent 64: 6

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer