Panniculitis infectious M79.3

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

infectious panniculitis; panniculitis infection

Definition
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Pathogen-induced inflammatory reaction of the subcutaneous fatty tissue. Frequently occurring in immunocompromised patients.

Pathogen
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  • Bacteria: Staphylococci, Streptococci, Pseudomonas, Klebsiellae, Yersinia, Tropheryma whippelii, Nokardia, Fusarium, Borrelia, Mycobacteria.
  • Fungi: Candia species, moulds, histoplasms, cryptococci, sporotrichia.

Etiopathogenesis
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Infection by direct inoculation of contaminated material or by septic metastases.

Clinical features
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Mostly painful, deep lying, inflammatory nodes with red skin overlying them. Tendency to abscess and fistula formation.

Histology
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Septolobular neutrophilic panniculitis in the acute stage. Later very different infiltrates depending on the pathogen spectrum.

Diagnosis
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Pathogen detection by smear, culture, PCR.

Differential diagnosis
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Panniculitides of other genesis.

Therapy
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Depending on the pathogen spectrum.

Literature
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  1. Morrison LK et al (2010) Infection and panniculitis.dermatol Ther 23: 328-340
  2. Patterson JW et al (1989) Infection-induced panniculitis. J CutanPathol 16:183-193

Incoming links (1)

Pseudomonas infections;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020