Paget, M. of the nipple. unilateral, symptom-free, therapy-resistant, red, painless, slowly growing plaque of the nipple existing for several months. In the meantime, extensive infiltration of the skin beyond the areola. Previously, there was an erythema of the nipple which did not heal under an anti-eczematous therapy.
Paget's disease, M. of the nipple. general view: intraepithelial localized, solitary or in groups situated atypical cells with large vesicular nuclei and distinct cytoplasmic border. the cells clearly distinguish themselves from the local keratinocytes. lymphoid cellular infiltrates are visible in the underlying dermis. between them numerous eosinophilic granulocytes are present.
Paget's disease, M. of the nipple. Detail enlargement: Intraepithelial localized, solitary or in groups located atypical cells with large vesicular nuclei and distinct cytoplasmic border. The cells clearly distinguish themselves from the local keratinocytes.
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