Oxybuprocaine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

4-amino-3-butoxybenzoic acid 2-diethylaminoethyl ester (IUPAC); Benoxinate; CAS number: 99-43-4

Definition
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Oxybuprocaine, a locally acting anaesthetic with the molecular formula C17H28N2O3 and a molar mass of 308.42 g-mol-1, is a local anaesthetic of the amis type (prototype is lidocaine) which is mainly used in ophthalmology and ear, nose and throat medicine. The substance is soluble in water as monohydrochloride.

Spectrum of action
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Oxybuprocaine is used for local inflammation of the throat and pharynx, often in combination with tyrothricin.

Indication
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Especially surface anesthesia of the cornea.

Standard concentration
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0.4-0.5% in eye drops.

Undesirable effects
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Allergies, corneal changes.

Preparations
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Novesine®, Benoxinate SE®, Conjuncain EDO®

Incoming links (1)

Local anaesthetics;

Outgoing links (2)

Local anaesthetics; Tyrothricin;

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Last updated on: 29.10.2020