DefinitionThis section has been translated automatically.
Rare, acquired, inflammatory skeletal disease, so far mainly described in children and adolescents, which is "dermato-osseous" associated with pustulosis palmo-plantaris and acne pustulosa in 20-30% of cases. S.a.u. SAPHO syndrome.
EtiopathogenesisThis section has been translated automatically.
Aetiopathologically, subacute to chronic recurrent, non-purulent, postinfectious triggered bone marrow inflammation is present.
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ManifestationThis section has been translated automatically.
Occurs in children, adolescents and young adults, especially in the female sex.
Clinical featuresThis section has been translated automatically.
Subacute, to chronically recurrent, non-purulent bone marrow inflammation of the clavicle, sternum, pelvis and spine. Association with pustulosis palmo-plantaris, acne conglobata and acne fulminans.
LiteratureThis section has been translated automatically.
- Dihlmann W, Herring L, Bargon GW (1988) The acquired hyperostosis syndrome (AHS). Progress Röntgenstr 149: 386-391
- Köhler H, Uehlinger E, Kutzner J et al (1975) Sterno-costoclavicular hyperostosis. Dtsch med Wschr 100: 1519-1523
- Schilling F, Kessler S (2000) The SAPHO-Syndrome: Clinical - rheumatological and radiological differentiation and classification of a patient of86 cases. Z Rheumatol 59: 1-28
- Schilling F (1991) Pustulous arthroosteitis. Dermatologist 42: 194-197
- Suei Y et al (2003) Diagnostic points and possible origin of osteomyelitis in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a radiographic study of 77 mandibular osteomyelitis cases. Rheumatology 42: 1398-1403
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Sapho syndrome;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer