Onycholysis totalis L60.13

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Onychomadese; Onychomadesis; Onychomadose; total onycholysis

Definition
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Onycholysis with complete detachment of the entire nail plate from the matrix region (Hardin J et al. 2015), whereby the detached nail is usually replaced by a new one. The abrupt dystrophic disturbance of the nail can also be understood as the maximum form of Beau-Reile's transverse furrows.

Etiopathogenesis
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Multifactorial genesis:

  • Infection-allergic, e.g. after scarlet fever, Coxsackie virus infections, varicella, purulent paronychia and other infectious diseases
  • after traumatisation
  • Drug-induced (chemotherapeutics, antiepileptics, antibiotics, lithium, gold preparations)
  • in association with other diseases such as Alopecia areata, Lichen planus, erythroderma, Lyell syndrome
  • Systemic diseases (mycosis fungoides, Stevens-Johnson syndrome, TEN, Kawasaki syndrome; peritoneal dialysis)

Therapy
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S.u. the respective clinical picture, s.a. Onycholysis semilunaris.

Literature
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  1. Hamm H et al (2018) Diseases of the nails. In: Braun-Falco`s Dermatology, Venerology Allergology G. Plewig et al. (Hrsg) Springer Verlag S 1388-1389
  2. Hardin J et al (2015) Onychomadesis: literature review. Br J Dermatol 172:592-596.
  3. Salgado F et al (2017) Shedding light on onychomadesis.Cutis 99:33-36.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020