Nimorazole

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Chemotherapeutic agent of the imidazole type.

Half-life
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3 h

Indication
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Trichomoniasis, amoebiasis, lambliasis.

Limited indication
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Blood formation disorders, application > 10 days, active CNS diseases, severe liver and kidney diseases.

Dosage and method of use
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  • Amoebiasis, Lambliasis: 2 times 1 g/day p.o. for 5-7 days; children 20-30 mg/kg bw/day.
  • Trichomoniasis: 4 times 500 mg/day p.o. for 7 days (partner treatment!).

Undesirable effects
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Allergic reactions, potential carcinogenicity, headache, fatigue, agitation, dizziness, metallic taste, leukopenia, gastrointestinal disorders.

Interactions
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Reduced alcohol tolerance, increased bleeding tendency when taking coumarins.

Contraindication
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Pregnancy, lactation, imidazole hypersensitivity.

Preparations
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Esclama

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Amebiasis; Lambliasis;

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Last updated on: 29.10.2020