Niclosamide

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Pharmacodynamics (Effect)
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Vermicide by depletion of glucose and glycogen, inhibition of glycolysis.

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Spectrum of action
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Taenia saginata, taenia solium, Diphyllobothrium latum, Hymenolepsis nana.

Indication
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Taeniasis, infections with Diphyllobothria

Note! Niclosamide is not effective against larval stages ( cysticercosis

)!

Limited indication
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Pregnancy (strict indication in the 1st trimester).

Dosage and method of use
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  • Adults and children > 6 years: 2 g as ED p.o.
  • Children 2-6 years: 1 g.
  • Children < 2 years: 500 mg.

Undesirable effects
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Headaches, gastrointestinal disorders, allergic reactions.

Interactions
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Reduced alcohol tolerance.

Preparations
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Yomesan

Patientinformation
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Remember! Take tablets at once unchewed or swallowed in water after breakfast. In case of constipation, ensure that the bowels are emptied before treatment!

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Last updated on: 29.10.2020