Nevus melanocytic acral D22.L

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Palmo-plantar located nevus. It has a special position, because the clinic is often difficult to distinguish from a malignant melanoma.

Clinical features
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Light brown to dark brown colored, usually blurred, with filiform runners reaching into the groin structures, spots, plaques or papules.

Histology
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Melanocytic nevus of the junctional or compound type. Detection of individual melanocytes, mostly formed in nests, in the area of the junctional zone and the entire surface epithelium. Typical is the release of melanin and melanocytes into the higher epithelial layers and into the str. corneum. The dermal tumor colonization is generally low. Melanocytes show clear "maturation" downwards. No mitoses!

Differential diagnosis
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Therapy
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No therapy necessary; excision is only indicated in cases of serious suspicion of malignancy.

Progression/forecast
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The risk of degeneration is generally no greater than that of naevi located elsewhere.

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Last updated on: 29.10.2020