DefinitionThis section has been translated automatically.
(Arabic: footnote). In medicine generally defined as the lowest value of (measured) values, e.g. the viral load, blood pressure or PSA value. The term nadir has its special meaning in chemotherapy, e.g. in the therapy-induced maximum reduction of leukocytes (leukocyte-nadir) or neutrophil granulocytes (granulocyte-nadir). The nadir is in most cases a dose-limiting factor for therapy.
Prof. Dr. med. Peter Altmeyer