Mucus penetration test
Synonym(s)
Post-coital test; Short Rock Miller Test; Sims Chicken Test
DefinitionThis section has been translated automatically.
In vitro test to assess the progressive motility of sperm in human or bovine cervical mucus at the time of ovulation.
IndicationThis section has been translated automatically.
Gynaecological-andrological indication for mainly immunological sterility factors. Antibody detection in women also by RAST.
ImplementationThis section has been translated automatically.
- Sims-Huhner test (post-coital test, sperm incompatibility test): Post-coital collection of female cervical mucus in which several spermatozoa move progressively in the presence of physiological findings,
- Kurzrock-Miller test (crossed mucus penetration test): Mixing of native ejaculate and cervical mucus of a sterile couple on the slide with each other and with ejaculate and mucus of a fertile couple, respectively, while assessing spermatozoid progressive motility in the mucus.
- Capillary-mucosal penetration test (Kremer test): incubation of small capillary tubes filled with ovulatory human cervical mucus in a native sperm reservoir on a graduated slide with assessment of migration distance in the mucus.
- Penetrak test: Industrially standardized variant of the Kremer test with biologically equivalent bovine cervical mucus; standard values are penetration distances of more than 30 mm in 90 minutes.
LiteratureThis section has been translated automatically.
- Alexander NJ (1981) Evaluation of male infertility with an in-viro cervical mucus penetration test. Fertility and Sterility 37: 823-827
- Chicken M (1914) The value of the spermatozoa test in sterility. Urol Cutan Rev (St. Louis) 18: 587-597
- Ola B et al (2003) Accuracy of sperm-cervical mucus penetration tests in evaluating sperm motility in semen: a systematic quantitative review. Hum Reprod 18: 1037-1046
- Sims HM (1888) Sterility and the value of microscope in its diagnosis and treatment. Transact Am Gynecol Soc (Boston) 13: 291