Microlivedo, acral - Altmeyers Encyclopedia

Definition
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Cutaneous manifestation of the so-called phospholipid-antibody syndrome (s.a. phospholipid antibodies) with blurred, bizarrely configured, livid skin changes on the acres, which can ulcerate and be very painful; s.a. livedo racemosa, livedovasculopathy

Proliferation of the small and medium-sized vessels of the dermis, numerous thrombosed capillaries and venules, no vasculitis.

Dermatology

Painful granulation tissue at the pressure points of the temples.

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Clinic, histology, laboratory (increase in phospholipid antibody levels).

Grob JJ et al (1991) Unfading acral microlivedo. A discrete marker of thrombotic skin disease associated with antiphospholipid antibody syndrome. J Am Acad Dermatol 24: 53-58
Scheinfeld NS et al (2003) Reticulate and stellate acral pigmentation associated with systemic lupus erythematosus and high titers of circulating anticardiolipin antibodies: a possible association with acral microlivedo. J Drugs Dermatol 2: 674-676
Wolf P et al (1992) Acral microlivedo - A clinical symptom of antiphospholipid syndrome. Z Hautkr 67: 714-717