Mesalazine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 05.02.2023

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Definition
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Half-life
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0,5-2,4 h or 6-9 h (metabolites).

Pharmacodynamics (Effect)
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Inhibitor of prostaglandin and leukotriene synthesis, anti-inflammatory and immunosuppressive.

Indication
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Chronic inflammatory bowel diseases, aphthae (topical application)

Dosage and method of use
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  • Tbl.: 3-4 times/day 500-1000 mg/day p.o.
  • Clysmes: 1 time per day before bedtime give the contents of 1 enema bottle as an enema into the intestine.
  • Rectal foam: 1 time per day before bedtime 2 sprays (= 10 g foam) into the intestine.

Standard concentration
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Rectal foam: 20%.

Preparations
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Claversal®500mg, Salofalk® 500 mg, Pentasa® 500 mg; 1000 mg

Outgoing links (1)

Sulfonamides;

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Last updated on: 05.02.2023