Mequitazine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Half-life
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18 h

Indication
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Limited indication
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Respiratory disorders, blood count disorders, intestinal stenosis, depression, narrow-angle glaucoma, heart disease, alcohol or drug intoxication, severe liver or kidney disease, prolactin-dependent tumours, Parkinson's syndrome, pheochromocytoma, prostate hypertrophy.

Dosage and method of use
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  • Adults/teenagers: 2 times/day 5 mg p.o.
  • Children 23-29 kg bw: 2 times/day 3,75 mg p.o.
  • Children 18-22 kg bw: 2,5 mg in the morning, 3,75 mg in the evening.
  • Children 13-17 kg bw: 2 times/day 2,5 mg p.o.
  • Children 10-12 kg bw: 1,25 mg in the morning, 2,5 mg in the evening.

Undesirable effects
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Paragroup allergy (juice), allergic reactions, anhidrosis, photosensitization, reduced reactivity, fatigue, hallucinations, headaches, rigor, tardive dyskinesia, Parkinson's syndrome Accommodation disorders, storage in cornea or lens, narrow angle glaucoma, cataract, dizziness, tachycardia, agranulocytosis, cholestasis, paralytic ileus, dry mouth, constipation, gastrointestinal disorders.

Interactions
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See Table 1.

Contraindication
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Paragroup allergy (juice), hypersensitivity to the active substance, pregnancy, lactation, children < 2 years.

Preparations
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Metaplexan

Tables
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Major interactions of Mequitazine

Alcohol

CNS cushioning ↑

Anticholinergics

anticholinergic effect ↑

Antidepressants, tricyclic

CNS cushioning ↑

Barbiturates

CNS cushioning ↑

Benzodiazepines

CNS cushioning ↑

Hypnotics

CNS cushioning ↑

Neuroleptics

CNS cushioning ↑

Sedatives

CNS cushioning ↑

Authors

Last updated on: 29.10.2020