Melanoma, malignant, nodular, solitary, solid, sharply defined, surface smooth, non-hairy, black speckled, symptomless lump, growing for more than a year, foundduring routine examination (lump has always been there). Incident light microscopy revealed strong grey-blue streaks and massive pigment network break-ups.
Melanoma, malignant, nodular, " always present", solitary, asymptomatic, growing for more than a year, coarse, largely symmetrical node with atropically shiny surface,
Melanoma, malignant, nodular, " always present", solitary, for years without symptoms, constantly weeping and also bleeding for 2 months, coarse, largely symmetrical, ulcerated lump with shiny surface.
Melanoma, malignant, nodular. Malignant melanoma of the primary nodular type. Over the last few months, surface and thickness growth. "Been wet before." Dark brown-black, smooth-surfaced (like polished) lumps. Arrow-marked satellite metastases shimmering bluish through. Encircling a capillary angioma.
Melanoma, malignant, nodular: Rapid growth in thickness in the last few months "I have already wet and bled once" (see further explanation in the following figure)
Melanoma, malignant, nodular: Rapid growth in thickness in the last few months. "I have already wet and bled once". Indicated by arrows: satellite metastases. Encircled: weeping areas of the surface (tumor parenchyma has destroyed the surface epithelium at these sites). A simple melanocytic nevus is marked by a square.
Melanoma, malignant, nodular. malignant melanoma of the primary-nodular type with satellite filia left pectoral in a 43-year-old man. in the last months surface and thickness growth. chronic, since youth existing, 2 x 1 cm, asymmetrical, irregularly limited, clearly raised, dark brown-black plaque of medium-rough consistency. coarse, partly nodular surface. no crustal deposit, no ulceration.
Melanoma, malignant, nodular. 26-year-old woman was diagnosed with an incidental finding on the back of a solitary, coarse, asymmetrical, pearl-like bordered plaque, measuring 8 x 8 mm and increasing for more than one year. The plaque was pigmented brown-black especially at the edges with a whitish-grey centre and central scaly ruffs. Strong grey-blue streaks and massive pigment network break-offs were visible peripherally under reflected light microscopy.
Melanoma, malignant, nodular. Malignant melanoma of the primary nodular type. In the last months area and thickness growth. Wetting and bleeding from time to time. Asymmetrical, irregular and blurred, clearly raised, dark brown-black lump of medium-rough consistency. Crustal deposits.
melanoma, malignant, nodular. malignant melanoma of the primary-nodular type (detailed picture). in the last months surface and thickness growth. asymmetrical, irregular and blurredly limited, clearly raised, dark brown-black nodule of medium-rough consistency. crustal deposits.
Melanoma malignant nodular. reflected light microscopy from the peripheral area of the node. homogeneous blue-grey-black discoloration in the centre. radial streaming.
Melanoma, malignant, nodular. Malignant melanoma of the primary nodular type. In the last months area and thickness growth. Has repeatedly oozed and bled. Asymmetrical, irregularly limited, clearly raised, dark brown-black ulcerated node with plaque-like base.
Melanoma, malignant, nodular. on UV-damaged skin, reddish-brown nodule with smooth, parchment-like surface. at the base spread of an irregularly configured and pigmented plaque.
Melanoma, malignant, nodular. reflected-light microscopy: Pigment-free nodule with red dot-shaped pigmentation (dots correspond to irregular vascular clusters). Very restless (no longer organic) pigment structures, with planar basic pigmentation, showing pseudopodia and radial streaking.
Melanoma malignes, nodular: A solitary node that has existed for years, has been growing for more than a year, is firm, sharply defined, smooth on the surface, not hairy, and has bled repeatedly in recent weeks.
Melanoma, malignant, nodular: in the centre of the lesion of red surface smooth nodules with peripheral growth, here formation of small clots which are no longer distally connected to the primary tumour (satelliteosis).
melanoma, malignant, nodular. solitary, since 1-2 years existing, ca. 0.8 cm in diameter, completely without symptoms, firm lump in a 47-year-old woman. the lump is centrally and on the right side black-brown crusty bordered. on the left side a brown-red, smooth surface is visible. since 6 months increase in size and occasional small bleedings with subsequent accumulation of blood crusts.
Melanoma malignant nodular: Cornu cutaneum-like malignant melanoma which was found only after shaving.
Melanoma, malignant, nodular. solitary, chronically active, growing rapidly in the last 4 weeks, occasionally bleeding slightly, 0.7 cm high, smooth, black lump on brown plaque.
Melanoma, malignant, nodular. reflected light microscopy: Nodular malignant melanoma with "polypoid" and "verrucous" surface Clark Level II, TD 0.65 mm, with comedo-like brownish to brown-black horn plugs, individual ectatic capillaries and grey-blue opaque zones (tumour diameter 4 mm).
Melanoma, malignant nodular (naevogenousmalignant melanoma) on the floor of a congenital melanocytic nevus.
melanoma, malignant, nodular. compact tumor formations in the upper and middle dermis. no maturation to depth. discontinuous tumor clusters at the base in dense lymphocytic infiltrate. imaging of tumor cells with the antigen MART.
Melanoma, malignant, nodular. atrophic epithelium, orthokeratosis, dressings of atypical, epitheloid melanocytes in the upper and middle dermis. conspicuous nuclear polymorphism. No "maturation" of the melanoyceae at the base.
Melanoma, malignant, nodular. detailed picture: nest formations of atypical melanocytes, partly pigmented partly unpigmented. large epithelioid cells, with hyperchromatic nuclei, nuclear polymorphism. numerous mitoses.
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