Melanokerasoma

Melanokerasoma is a postulated model that assumes that melanin in keratinocytes is surrounded by three membranes: the melanosome membrane and the membranes derived from the plasma membranes of melanocytes and keratinocytes. In a further step, the newly formed melanokerasomes fuse with lysosomes and form a phagolysosome, which leads to the degradation of all three inner membranes. Finally, the melanized phagolysosome disintegrates into smaller vesicles containing aggregates or individual melanin granules distributed in the cytoplasm.

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