HistoryThis section has been translated automatically.
Bloch, 1927; Mishima and Pinkus, 1960
DefinitionThis section has been translated automatically.
Mixed tumor in which melanocytes and keratinocytes proliferate evenly; variant of the pigmented acanthotic Verruca seborrhoica.
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ManifestationThis section has been translated automatically.
In adults, usually occurring after the 40th LJ.
Clinical featuresThis section has been translated automatically.
Deeply pigmented, slow-growing, wart-like tumour which is indistinguishable from Verruca seborrhoica.
HistologyThis section has been translated automatically.
Proliferation of basaloid epithelial cells, melanocytes distributed over all layers of the tumor and numerous melanophages in the dermis.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Melanoacanthoma is usually a histological diagnosis by chance. Since it was removed in toto either under the suspected diagnosis "malignant melanoma" or "pigmented verruca seborrhoica", further surgical measures of this benign tumor are not necessary. If necessary, the residual tumor can be cured in LA.
Progression/forecastThis section has been translated automatically.
Benign.
LiteratureThis section has been translated automatically.
- Bloch B (1927) On benign, non-naevoidal melanoepitheliomas of the skin together with remarks on the nature and genesis of dendrite cells Arch Dermatol Syph (Berlin) 153: 20-40
- Mishima Y, Pinkus H (1960) Benign mixed tumor of melanocytes and malpighian cells. Arch Dermatol 81: 539-550
- Fornatora ML et al (2003) Oral melanoacanthoma: a report of 10 cases, review of the literature, and immunohistochemical analysis for HMB-45 reactivity. At J Dermatopathol 25: 12-15
- Vion B et al (1989) Melanoacanthoma of the penis shaft. Report of a case. Dermatologica 179: 87-89
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Outgoing links (6)
Keratinocyte; Keratosis seborrhoeic (overview); Local anesthesia; Melanocyte; Melanoma cutaneous; Melanophages;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer