Melan-a

Melan-A(MART1) serves as an important immunohistological marker for melanocytes and melanocytic tumors. The available antibody is more sensitive than HMB45.
The detection of Melan-A is positive in epidermal and dermal melanocytes, in steroid-producing cells (adrenal gland) and in cutaneous clear cell sarcoma.

1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 30.
2. Takamura S et al. (2015) Case of clear cell sarcoma in the left buttock in which serum neuron-specific enolase was a useful marker for monitoring disease progression. J Dermatol 42:621-624.
3. Tazzari M et al (2015) Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report. BMC Cancer 15:58.