Medroxyprogesterone acetate
Definition
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Half-life
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24-50 h or 30-40 days (with i.m. application).
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Indication
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Amenorrhoea.
Limited indication
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Preparation for surgery (stop 12 weeks before surgery), otosclerosis, phlebitis, smokers > 30 years.
Dosage and method of use
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Hormone therapy: 5-10 mg/day p.o. in combination with oestrogens from the 16th to 26th day of the cycle; hormonal contraception: 150 mg during the first 5 days of the cycle deep i.m., repeated every 3 months.
Preparations
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Clinofem, Farlutal
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Prof. Dr. med. Peter Altmeyer