Marginal vein persistentI87.2

Angiodysplasia with varicose changes due to an abnormal regression of a lower limb embryonic vein in embryogenesis.

In terms of etiopathogenesis, an embryonic marginal vein can be defined as an "embryonic, valveless venous system (V.marginalis fibularis) of the lower extremity" (embryonic vein), which regresses during embryogenesis, after the deep venous system has been established. Embryonic developmental disorders can lead to the persistence of this varicose venous system, which can develop on the outer side of the lower leg up to the proximal thigh (general stripe). The persistence of this embryonic venous system is often combined with hypo- or aplasia of the deep veins and accompanying or directly draining AV fistulas.

In larger studies with persistent embryonic marginal veins, varicosis was found in 31% of cases in the area of the great saphenous vein, 46% in the area of the paravian saphenous vein, 64% in the area of the lateral branches and 16% in the area of the femoropoplitealis. In Klippel-Trénauney syndrome, a pesicidal original vein was found in 17% of cases.

Surgical rehabilitation by extirpation of the vein, if necessary in combination with foam sclerotherapy, is recommended.

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2. Oduber CE et al (2013) The persistent embryonic vein in Klippel-Trenaunay syndrome. Vasc Med 18:185-191.

3. Vollmar JF et al. (1979) Vena marginalis lateralis persistens - the forgotten vein of angiologists. VASA 8:192-202

4. Wagner A (2010) Physiology and pathophysiology of venous hemodynamics. In: T Noppeney, H Nüllen Diagnosis and Therapy of Varicosis. Springer Medicine Publishing House Heidelberg S 52 -60