Lymphadenopathy, dermatopathicI89.8

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

dermatopathic; dermatopathic lymphadenitis; dermatopathic lymphadenopathy; Lipomelanotic reticulosis; Lymphadenitis; Lymphadenitis dermatopathic; lymphadenopathia dermatopathica lipomelanotica; Lymphogranuloma pigmented with generalized skin appearance; maladie de Pautrier-Woringer; Pautrier-Woringer disease; Pautrier-Woringer-Melano-Reticulosis; pigmented lymphogranuloma with generalized skin appearance; reticulose lipo-mélanique; Reticulose lipo-mélanique (Pautrier; Woringer)

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HistoryThis section has been translated automatically.

Pautrier and Woringer, 1932

DefinitionThis section has been translated automatically.

Localized or generalized swelling of lymph nodes as a concomitant symptom of various, mostly generalized skin diseases, e.g. generalized eczema, mycosis fungoides, erythroderma, in (melano-) erythroderma, in generalized lichen planus, generalized psoriasis.

Clinical featuresThis section has been translated automatically.

Swelling of lymph nodes, especially inguinal and axillary. Skin symptoms corresponding to the underlying disease.

HistologyThis section has been translated automatically.

Lymph follicles with large germinal centers, central reticulum cell proliferation, lipoid storage, melanin and hemosiderin deposition.

Differential diagnosisThis section has been translated automatically.

TherapyThis section has been translated automatically.

Treatment of the underlying disease.

Progression/forecastThis section has been translated automatically.

Recovery after healing of the underlying disease.

LiteratureThis section has been translated automatically.

  1. Geissmann F et al (2002) Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin. J Exp Med 196: 417-430
  2. Pautrier LM, Woringer F (1937) La réticulose lipo-mélanique. Ann Derm 7 sér 8: 257-273
  3. Pautrier LM, Woringer F (1932) Note préliminaire sur un tableau histologique particulier de lésions ganglionnaires accompagnant des éruptions dermatologiques généralisées prurigineuses de types cliniques différents. Bull Soc Franc Derm Syph 39: 947-955
  4. Vonderheid EC, Diamond LW, Lai SM et al (1992) Lymph node histopathologic findings in cutaneous T-cell lymphoma. A prognostic classification system based on morphologic assessment. Am J Clin Pathol 97: 121-129

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Last updated on: 29.10.2020