LRMDA Gene

Last updated on: 21.06.2022

Dieser Artikel auf Deutsch

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

The LRMDA gene (LRMDA stands for "Leucine Rich Melanocyte Differentiation Associated") is a protein-coding gene located at gene locus 10q22.2-q22.3. Alternatively spliced transcript variants have been identified.

General informationThis section has been translated automatically.

The LRMDA gene encodes a leucine-rich repeat protein. The encoded protein is thought to play a role in melanocyte differentiation.

Mutations in this gene have been associated with autosomal recessive oculocutaneous albinism 7 (OCA7) (Gronskov K et al. 2013).

LiteratureThis section has been translated automatically.

  1. Gronskov K et al. (2013) Mutations in C10orf11, a melanocyte-differentiation gene, cause autosomal-recessive albinism. Am. J. Hum. Genet. 92: 415-421.
  2. Montoliu L et al. (2013) Increasing the complexity: new genes and new types of albinism. Pigment Cell Melanoma Res. 27: 11-18.

Last updated on: 21.06.2022