Lopinavir

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Pharmacodynamics (Effect)This section has been translated automatically.

Inhibitor of the HIV-associated protease.

IndicationThis section has been translated automatically.

Combination therapy of HIV infection.

Dosage and method of useThis section has been translated automatically.

  • Adults and adolescents: 2 times/day 2 tablets (400 mg Lopinavir/100 mg Ritonavir); alternatively 2 times/day 5 ml solution. (juice).
  • Children > 2 years: according to the manufacturer's technical information.

Undesirable effectsThis section has been translated automatically.

Diarrhea, weakness, fatigue, headache, nausea, pancreatitis, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, lipodystrophy syndrome.

Notice! In case of liver diseases, e.g. hepatits B or C, there may be a deterioration of liver function.

InteractionsThis section has been translated automatically.

Interactions are possible with simultaneous use of triazolam, astemizole, pimozide, dihydroergotamine, cisapride, propafenone, terfendadine, flecainide, midazolam, rifampin, St. John's wort.

PreparationsThis section has been translated automatically.

Kaletra (combination with ritonavir)

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Last updated on: 29.10.2020