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Lipoma chondroides

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

chondroid lipoma

Definition
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Rare, benign, slow-growing, painless adipose tissue tumor located in deep soft tissue or subcutaneously, showing aspects of both embryonic adipose tissue and embryonic cartilage tissue.

Occurrence/Epidemiology
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Adult women are affected predominantly, children less frequently.

Localization
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Extremities, rarely trunk or head and neck area, oral cavity (tongue)

Histology
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Lobular, encapsulated tumour consisting of mature adipocytes, numerous lipoblasts and granular, multivacuolar eosinophil cells embedded in a partly myxoid, partly chondroid stroma. Often a chromosomal t(11;16)(q13;p13) translocation with a C11orf95-MKL2 fusion is detectable.

Literature
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  1. Choi DL et al (2013) A painless right supraclavicular mass. Chondroid lipoma (CL). JAMA Otolaryngol Head Neck Surg 139:1069-1070.
  2. Flucke U et al (2013) Presence of C11orf95-MKL2 fusion is a consistent finding in chondroid lipomas: a study of eight cases. Histopathology 62: 925-930.
  3. Thway K et al (2012) Chondroid lipoma: an update and review. Ann Diagn Pathol 16:230-234.
  4. Villarroel Dorrego M et al (2014) Chondroid lipoma of the tongue: a report of two cases. Oral Maxillofac Surgery 18:219-222.
  5. Yaranal PJ et al (2013) Chondroid lipoma of the thigh: a report of two cases. Indian J Pathol microbiol 56:464-465.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020