Lipoatrophy, localized after glucocorticosteroid injectionsT88.7

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 12.05.2021

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Synonym(s)

Cortisone atrophy; Fatty tissue atrophy; Fatty tissue loss; Glucocorticosteroid lipodystrophy; Lipatrophy; localized lipatrophy; localized lipatrophy after medication; localized lipodystrophy; Steroid atrophy

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DefinitionThis section has been translated automatically.

Mostly reversible atrophy of cutis and subcutis after injection of glucocorticoid crystal suspension; rarely also after application of fluorinated glucocorticosteroids in occlusive dressing. Pancreatic panniculitis also heals under laoclized adipose tissue atrophy.

EtiopathogenesisThis section has been translated automatically.

Especially in combinations of glucocorticoid injections with pressure, e.g. occurring in keloid treatment, in some cases a stronger crystal suspension density seems to play a role in case of incorrect injection technique (too low in intradermal or too high in intramuscular injection).

ManifestationThis section has been translated automatically.

Almost exclusively observed in women or girls, less frequently in male adolescents.

LocalizationThis section has been translated automatically.

Place of injection, usually thigh, buttocks or upper arm.

Differential diagnosisThis section has been translated automatically.

TherapyThis section has been translated automatically.

Waiting. Mostly regression within 1-3 years. Residual skin atrophy with hypopigmentation and telangiectasia.

Progression/forecastThis section has been translated automatically.

Mostly regression within 1-3 years.

LiteratureThis section has been translated automatically.

  1. Süss R et al (1992) Skin atrophy after intralesional glucocorticosteroid injection under the image of linear circumscript scleroderma. Act Dermatol 18: 247-248

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Last updated on: 12.05.2021