Lichen planus e medicatione L43.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 03.08.2023

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Definition
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Lichen planus triggered or induced by medications. The following medications can trigger lichen planus:

  • Gold salts
  • Antimalarials
  • Arsenic compounds
  • Beta-blockers (non-ACE inhibitors)
  • diuretics
  • Antibiotics
  • NSAIDS
  • Phenothiazines
  • Heavy metals
  • Analgesics(naproxen -Güneş AT et al. 2006)
  • Denosumab (antibody approved as an osteoporosis drug). Lichen planus occurs a median of 3-4weeks after application of the antibody (Boyd I 2016).
  • TNF- alpha inhibitors ( McCarthy M et al. 2015).

Therapy
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Discontinue or transfer the triggering medication, otherwise according to the Lichen planus.

Literature
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  1. Boyd I (2016) Denosumab and lichen planus WHO Pharmaceutical Newsletter 6: 155.
  2. Clayton R et al (2010) Mucosal and vulval) lichen planus in women: are angiotensin-converting enzyme inhibitors protective, and beta-blockers and non-steroidal anti-inflammatory drugs associated with the condition? Clin Exp Dermatol 35:384-387.
  3. Gorouhi F et al (2014) Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. ScientificWorldJournal doi:10.1155/2014/742826.
  4. Güneş AT et al (2006) Naproxen-induced lichen planus: report of 55 cases. Int J Dermatol 45:709-712.

  5. McCarty M et al (2015) Lichenoid Reactions in Association with Tumor Necrosis Factor Alpha Inhibitors: A Review of the Literature and Addition of a Fourth Lichenoid Reaction. J Clin Aesthet Dermatol 8:45-49.
  6. Zaraa I et al (2013) Lichen planus pemphigoides: four new cases and a review of the literature. Int J Dermatol 52:406-412.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 03.08.2023