Lichen planus bullosus L43.10

Rare variant of lichen planus with blistered transformation of lichen planus nodules (Liakopoulou A et al. 2017)

Autoimmunologic disease; etiology mostly unknown. Triggering drugs have been described (Ozkan S et al. 1999/ Naproxen)

Occurring at any age. Also in children. The oral lichen planus occurs as a blistered variant in about 2-3% of those affected.

Extremities, also oral mucosa.

Image of typical lichen planus with subepidermal blistering in the subepithelial clefts already preformed by Joseph's spaces. This form must be distinguished from lichen planus pemphigoides, which is regarded as a coincidental disease entity of lichen planus and bullous pemphigoid.

No proof of BP180-AK; no proof of BP 230-AK. Detection of fibrinogen deposited in the form of a band.

Lichen planus pemphigoides: Coincidence of lichen planus and bullous pemphigoid (bP). Detection of bP-AK in lesional and non-lesional skin.

Bullous pemphigoid: Urticarial papules, subepithelial blisters; no evidence of typical lichen planus efflorescences. Detection of bP-AK.

Dermatitis herpetiformis: Disseminated, very itchy/burning or stinging/painful, 0.1-0.2 cm large, grouped, reddened papules, also vesicles, which erode quickly. This colorful efflorescence spot purri is mainly detectable in the area of the elbows and buttocks.

In case of minor blistering, potent glucocorticoid ointments(e.g. Dermoxin, Ecural), otherwise mild local care therapy (e.g. with Ungt. emulsif. aquos. or ^Asche® Basis Creme).

Corresponding to lichen planus. Successful treatment has been reported with a combination of glucocorticoids and dapsone (e.g. dapsone-fatol).

An association with chronic hepatitis B seems to be detectable above average.

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