Lichen myxedematosus and HIV-Infection L98.5

The coincidence of lichen myxoedematosus and HIV infection is reported with above-average frequency. Frequently, these are pronounced forms of this cutaneous mucinosis.

An etiopathological relationship between lichen myxoedematosus and HIV infection may be assumed on the basis of the available publications. Publications of REM syndrome, scleroedema adultorum (Yachoui R et al. 2013), and HIV infection should also be considered in this context.

Theassociation of scleromyxedema with chronic hepatitis C was drawn attention by Chen KY et al 2019. A total of 28 patients were diagnosed with lichen myxoedematosus (1x generalized, 27 x localized or atypical forms). The prevalence of hepatitis C was 6.5 times higher in this clientele than in the general population (Chen KY et al. 2019).

1. Abbott RA et al. (2010) Widespread papules in a patient with human immunodeficiency virus. Papular mucinosis (PM) in association with HIV infection. Clin Exp Dermatol 35:801-802.
2. Chen KY et al (2019) Scleromyxedema and lichen myxedematosus: Is it associated with viral hepatitis? J Dermatol 46:879-885.
3. Girón J et al (2007) Resolution of papular mucinosis in a person with HIV infection. AIDS Read 17:418-420.
4. Guarda NH et al (2023) Case for diagnosis. Multiple infiltrated plaques in a patient with human immunodeficiency virus and hepatitis C co-infection: lichen myxedematosus. An Bras Dermatol 98:398-400.
5. Rongioletti F et al (1998) Cutaneous mucinoses and HIV infection. Br J Dermatol 139:1077-1080.
6. Temelkova I et al. (2019) Scleromyxedema (Arndt-Gottron Syndrome) Developing Under Tenofovir Treatment for Hepatitis B: Unique Presentation in a Bulgarian Patient! Open Access Maced J Med Sci 7:782-785.
7. Tenea D et al (2023) Reticular erythematous mucinosis in an African woman with HIV infection: case report and literature review. Case Rep Dermatol 15:117-125.
8. Wada N et al (2016) Case of cutaneous mucinosis with HIV infection. J Dermatol 43:833-834.
9. Yachoui R et al (2013) Scleredema in a patient with AIDS-related lipodystrophy syndrome. Case Rep Endocrinol 943798. doi: 10.1155/2013/943798.