Leydig cell insufficiency, postpubertalE23.0
DefinitionThis section has been translated automatically.
Androgen deficiency due to reduced pituitary LH/ICSH of unknown etiology; androgen-dependent strongly reduced fructose concentration in the ejaculate with strongly reduced fertility (see fertility disorder); otherwise normal male habitus, normal testicular size and normozoospermia.
TherapyThis section has been translated automatically.
Hormone substitution with HCG (e.g. Predalon) 5000 IU/week i.m. and HMG (e.g. Menogon) 3 times/week 150 IU until normalization of fructose in the ejaculate. If necessary, testosterone substitution with testosterone nantate (e.g. Testoviron depot 50), initial 50 mg/month i.m., slowly increase dose within 1-2 years to 250 mg/month i.m.