LeuködemK13.2

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Leukoedema; Smoker's leukemia

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HistoryThis section has been translated automatically.

Sandstead & Lowe 1935

DefinitionThis section has been translated automatically.

Irritant, mostly symmetrically occurring, reversible, whitishopal discoloration in the oral mucosa area, which can occur as a preliminary stage of leukoplakia (see below leukoplakia, oral).

Occurrence/EpidemiologyThis section has been translated automatically.

Worldwide prevalence varies: India 0.02%; New Guinea 16.9%; Sweden 4.9%.

EtiopathogenesisThis section has been translated automatically.

Mostly a consequence of smoking cigarettes or cigars. In the coloured population also among non-smokers (chewing irritating fruits, e.g. betel nuts).

LocalizationThis section has been translated automatically.

Cheek mucosa, tongue, lips, palate. In principle, leukoedema can also be observed in the genital mucous membranes.

Clinical featuresThis section has been translated automatically.

The oral mucosa appears whitish-cloudy, opalescent, but unchanged on palpation (no increase in consistency). If the leukoedema is more pronounced, there is a structural change of the surface with the formation of net-like wrinkles, which become particularly prominent when the mucosa is pushed together.

HistologyThis section has been translated automatically.

Hydropic cell ballooning down to the lower stratum spinosum.

TherapyThis section has been translated automatically.

Stop smoking or application of other mucous membrane irritants.

LiteratureThis section has been translated automatically.

  1. Canaan TJ, Meehan SC (2005) Variations of structure and appearance of the oral mucosa. Dent Clin North Am 49: 1-14
  2. Pindborg JJ et al (1968) Epidemiology and history of oral leukoplakia and leukoedema among Papuans and New Guineans. Cancer 22: 379-384
  3. Sandstead HR, Lowe JW (1953) Leukoedema and keratosis in relation to leukoplakia of the buccal mucosa in man. J Natl Cancer Inst 14: 423-437

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer