DefinitionThis section has been translated automatically.
Single, localized or disseminated, specific, macular, papular or nodular skin infiltrates in the different forms of lymphocytic leukemias.
Primarily seen in patients with B-cell type chronic lymphocytic leukemia (B-CLL).
Less frequently, specific skin infiltrates are seen in:
- acute lymphoblastic leukemia/lymphoma
- T-cell large lymphocytic leukemia
- prolymphocytic leukemia
- T-cell leukemia with large granular lymphocytes and
- hairy cell leukemia.
In most cases, specific skin infiltrates are found in the presence of pre-existing, hematologically oncologically proven underlying disease. Rarely they precede the manifest lymphatic systemic disease.
Differential diagnosisThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Parsi M et al (2021) Leukemia Cutis. 2021 Jul 21. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing PMID: 31082180.
- Robak E et al. (2021) Skin changes in hairy cell leukemia. Ann Hematol100: 615-625.
- Yang M et al. (2020) Chimeric antigen receptor-modified T-cell therapy for bone marrow and skin relapse Philadelphia chromosome-like acute lymphoblastic leukemia: A case report. Medicine (Baltimore) 99:e18639.
- Yagi H et al. (2003) Cutaneous type of adult T cell leukemia/lymphoma: a new entity among cutaneous lymphomas. J Dermatol 30: 641-643
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Outgoing links (5)
All, skin manifestations ; Chronic lymphatic leucemia, skin manifestations; Hairy cell leukemia; Large granular lymphocytic Leukemia; Leukaemias myeloic of the skin;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer