Lentigo maligna Images

Lentigo maligna: a slow-growing, completely symptom-free spot that has been known for years; histologically, no invasiveness (transition to lentigo maligna melanoma) could be detected even in cut series.

Lentigo solaris. solitary, chronically stationary, 0.8 x 0.6 cm large, sharply defined, inhomogeneously coloured, symptomless, brown, smooth spot. 74-year-old female patient with strong UV exposure.

Lentigo maligna: a slow-growing, heterogeneously pigmented, light to dark brown, asymmetrical spot with irregularly lobed edges on the left cheek of a 68-year-old woman with skin type I, known for several years.

Lentigo maligna: Reflected light microscopy. Irregular distribution of the pigment network.

Lentigo maligna. Irregularly limited and colored pigment spot on the face.

Lentigo maligna: 71-year-old patient, more than five years old, first light brown, then darkened, symptom-free, 1.4 x 0.8 cm, light brown to black-brown spot in actinically stressed skin.

Lentigo maligna with transition to a lentigo maligna melanoma: bizarrely configured brown spot with palpable induration in the distal part (darker colored).

Lentigo maligna with transition to a lentigo maligna melanoma: 68-year-old man, presenting in practice because of eczema. On questioning the completely symptomless "spot" on the earlobe has slowly grown over the years. Excision with histology: Both parts of a lentigo maligna and (central) parts of a lentigo maligna melanoma, TD 0.4mm, pT1a.

Lentigo maligna: multiple, chronically stationary, since more than 5 years existing, imperceptibly growing, irregularly limited, black-brownish, 0.3-2.0 cm large pigment spots on the right cheek of a 69-year-old man.

Histology: Epidermis atrophy, condensation of atypical melanocytes in the basal stratum, in places also in the spinal stratum.

lentigo maligna. detail enlargement: dense, linear melanocyte proliferation descending at the sweat gland outlet. isolated suprabasal melanocytes are visible. pigment incontinence and actinic elastosis are also present.

Lentigo maligna: penetration of the epithelium with bizarrely configured melanocytes; immunohistological presentation of the melanocytes (red) with the antibody Melan A.