Lenograstim

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Glycosylated granulocyte colony stimulating factor produced by recombinant DNA technology.

Indication
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Severe neutropenia in patients with non-myeloidal malignant diseases under cytostatic drugs.

Dosage and method of use
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150 μg/m2 KO s.c. or i.v. from the day following the chemotherapy until the expected low point is passed and the neutrophil count is normal Application max. 28 days.

Remember! Do not use 1 day before and on the day of chemotherapy because of the increased sensitivity of rapidly dividing myeloid cells!

Undesirable effects
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Alopecia, nausea, vomiting, fever, headache, bone pain, leukocytosis, thrombopenia.

Notice! Check your leukocyte and thrombocyte counts regularly!

Contraindication
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Pregnancy, lactation, simultaneous cytotoxic chemotherapy.

Preparations
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Granocyte

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Last updated on: 29.10.2020